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Freepik

Type
Brand name
Biochemical name
Route of Administration
Estrogen
Estrofem (1mg/2mg)
Estradiol Hemihydrate
Oral/Sublingual
Estrogen
Progynova
Estradiol Valerate
Oral/Sublingual
Estrogen
Climara
Estradiol Patches
Transdermal
Estrogen
Estradot
Estradiol Patches
Transdermal
Estrogen
Estramon
Estradiol Patches
Transdermal
Estrogen
Oestrogel
Estradiol Gel
Transdermal
Anti-androgen
Androcur
Cyproterone acetate (CPA)
Oral
Anti-androgen
Casodex
Bicalutamide
Oral
Anti-androgen
Aldactone
Spironoactone
Oral
Anti-androgen
Spirolon (25mg)
Spironoactone (Spiro)
Oral
Progesterone
Oral micronised progesterone
Oral/rectal

  • Breast growth
  • Softening of skin and hair
  • Reduced musculature and strength
  • Fat redistribution to hips and thighs
  • Increase in fat-to-muscle ratio
  • Thinning of facial and body hair
  • Slowed or stopped head hair loss
  • Decrease in size of testicles and genitalia
  • Decrease in bone density

  • Erectile dysfunction
  • Loss of ability to ejaculate
  • Loss of libido
  • Infertility
  • Weight gain
  • Mood swings
  • Depression
  • Increased risk of deep vein thrombosis
  • Increased breast cancer risk (when compared to cis men)
    • It is crucial to remain patient if you have yet to see any change.

    Effect
    Onset
    Completion
    Permanency
    Breast development
    2–6 months
    2–3 years
    Permanent
    Reduced and slowed growth of facial and body hair
    3–12 months
    >3 years
    Reversible
    Cessation and reversal of scalp hair loss
    1–3 months
    1–2 years
    Reversible
    Softening of skin and decreased skin oiliness and acne
    3–6 months
    Unknown
    Reversible
    Redistribution of body fat in a feminine pattern
    3–6 months
    2–5 years
    Reversible
    Decreased muscle mass and strength
    3–6 months
    1–2 years
    Reversible
    Widening and rounding of the pelvis
    Unknown
    Unknown
    Permanent
    Changes in mood, emotionality, and behaviour
    Immediate
    Unknown
    Reversible
    Decreased sex drive and spontaneous erections
    1–3 months
    3–6 months
    Reversible
    Erectile dysfunction and decreased ejaculate volume
    1–3 months
    Variable
    Reversible
    Decreased sperm production and infertility
    Unknown
    >3 years
    Mixed
    Decreased testicular volume
    3–6 months
    2–3 years
    Unknown
    Voice changes (e.g., decreased pitch/resonance)
    None
    N/A
    N/A
    Height changes (e.g., decrease)
    None
    N/A
    N/A

  • Facial feminisation surgery
  • Tracheal shaving
  • Breast augmentation
  • Bottom surgery

    • HRT may result in infertility — but it does not act as a form of contraception and you should take all necessary precautions.

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